Enzyme is a type of protein in cells that has an important role for the body. There are various types of enzymes for different functions. Lack of production of an enzyme can cause metabolic disorders that lead to serious illnesses. Enzymes play an important role in metabolic processes. Metabolism includes chemical reactions that occur in the body to produce energy, including breaking down fats, carbohydrates, and proteins. When the production or function of the enzyme is disrupted, the metabolic processes in the body are disrupted. Various diseases due to enzyme deficiency Metabolic disorders due to deficiency of various types of enzymes, one of which is metabolic disorders that are hereditary. Patients with this disorder generally experience symptoms in the form of decreased appetite, vomiting, jaundice (jaundice), weight loss, abdominal pain, fatigue, late growth, seizures, to coma. Symptoms of metabolic disorders due to enzyme deficiency, can appear gradually or suddenly, whi